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Tutorials and Reviews

Institute of Clinical Biometrics
  1. Center for Medical Data Science
  2. Institutes
  3. Institute of Clinical Biometrics
  4. Research
  5. Tutorials and Reviews

Contributing to interdisciplinary knowledge transfer, we have published a number of tutorials and reviews on the following topics:

Heinze G, Christensen J, Haller MC (2022): “Modeling pulse wave velocity trajectories-challenges, opportunities, and pitfalls.” Kidney Int 101(3): 459-462. doi:10.1016/j.kint.2021.12.025.

Gregorich M, Strohmaier S, Dunkler D, Heinze G (2021): “Regression with Highly Correlated Predictors: Variable Omission Is Not the Solution.” Int. J. Environ. Res. Public Health, 18(8): 12. doi:10.3390/ijerph18084259

Dunkler, D., Haller, M., Oberbauer, R. and Heinze, G. (2020): "To test or to estimate? P‐values versus effect sizes", Transpl Int, 33: 50-55. doi:10.1111/tri.13535

Heinze G, Wallisch C, Dunkler D (2018): "Variable selection - A review and recommendations for the practicing statistician", Biom J 60:431-449. doi:10.1002/bimj.201700067, Level: advanced

Mansournia MA, Geroldinger A, Greenland S, Heinze G (2018): "Separation in Logistic Regression: Causes, Consequences, and Control", Am J Epidemiol 187:864-870. doi:10.1093/aje/kwx299, Level: advanced

Heinze G, Dunkler D (2017): "Five myths about variable selection", Transplant International 30:6-10. doi:10.1111/tri.12895, Level: beginner

Boucquemont J, Heinze G, Jager KJ, Oberbauer R, Leffondre K (2014): "Regression methods for investigating risk factors of chronic kidney disease outcomes: the state of the art", BMC Nephrology 15:45-45. doi:10.1186/1471-2369-15-45, Level: beginner

Leffondre,K., Boucquemont,J., Tripepi,G., Stel,V., Heinze,G., Dunkler,D. (2014): "Analysis of risk factors associated with renal function trajectory over time: a comparison of different statistical approaches", ndt Nephrology Dialysis Transplantation, (published online), doi:10.1093/ndt/gfu320, Level: advanced

Leffondre,K., Jager,K.J., Boucquemont,J., Stel,V.S., Heinze,G. (2013): "Representation of exposures in regression analysis and interpretation of regression coefficients: basic concepts and pitfalls", Nephrology Dialysis Transplantation, 29 (10), 1806-1814. doi:10.1093/ndt/gft500, Level: beginner

Tripepi,G., Heinze,G., Jager,K.J., Stel,V.S., Dekker,F.W. & Zoccali,C. (2013): "Risk prediction models", Nephrology Dialysis Transplantation, 28, 1975-1980. doi:10.1093/ndt/gft095, Level: advanced

Heinze, G., Jüni, P. (2011): An overview of the objectives of and the approaches to propensity score analyses, European Heart Journal 32, 1704 ? 1708. doi:10.1093/eurheartj/ehr031, Level: advanced

Gleiss A, Oberbauer R, Heinze G (2018): "An unjustified benefit: immortal time bias in the analysis of time-dependent events", Transpl Int 31:125-130. doi:10.1111/tri.13081, Level: advanced

Gleiss A, Zeillinger R, Braicu EI, Trillsch F, Vergote I, Schemper M (2016): "Statistical controversies in clinical research: the importance of importance", Annals of Oncology 27:1185-1189. doi:10.1093/annonc/mdw159, Level: advanced

Stel VS, Heinze G, Tripepi G, Zoccali C, Jager KJ (2015): "Seven essential tools of a cardiologist's survival kit", International Journal of Cardiology 191:87-89. doi:10.1016/j.ijcard.2015.04.246, Level: beginner

Wolbers M, Koller MT, Stel VS, Schaer B, Jager KJ, Leffondre K, Heinze G (2014): "Competing risks analysis: objectives and approaches", European Haert Journal 35:2936-2941. doi:10.1093/eurheartj/ehu131, Level: advanced

Heinzl H (2009): "Kaplan-Meier-Kurven und die Hazard Ratio", krebs:hilfe! 2:X-XI. Full text PDF (German only), Level: beginner

Heinzl H (1998): "Flexible Beschreibung der Wechselwirkung zwischen einer binären zeitabhängigen Kovariablen und der Zeit im Cox'schen Modell am Beispiel von Transplantationsdaten", Berichte der GKC 21:31-36. Full text PDF (German only), Level: advanced

Schemper, M. & Smith, T. L. (1996): A note on quantifying follow-up in studies of failure time, Controlled Clinical Trials 17, 343-346. Full text PDF, Level: advanced

Heinzl H, Benner A (2019): "Three brief pieces of statistical advice for medical peer reviewers", Eur J Clin Invest. 49(11):e13171. doi:10.1111/eci.13171, Level: beginner

Gleiss A (2017): "Identifiability of Components of Complex Interventions Using Factorial Designs", J Altern Complement Med 23:569-574. doi:10.1089/acm.2017.0075, Level: beginner

Dunkler, D., Sanchez-Cabo, F., Heinze, G. (2011): "Statistical Analysis Principles for Omics Data", Chapter 5 in Bioinformatics for Omics Data (Hg.: Mayer, B.), Reihe: 719 - Methods in Molecular Biology, Humana Press

Mittlböck M (2009): Einführung in das statistische Testen, krebs:hilfe 2:2009:VI-VII. Full text PDF (German only), Level: beginner

Mittlboeck M (2008): "Critical Appraisal of Randomized Clinical Trials: Can We Have Faith in the Conclusions?", Breast Care 3:341-346. doi:10.1159/000157168 , Level: beginner

Heinzl H, Mittlböck M (2007): "Eine Einführung zu chirurgischen Lernkurvenstudien", Forum der Medizin_Dokumentation und Medizin_Informatik 1/2001:30-33. Full text PDF (German only), Level: beginner

Draxler W, Mittlböck M (2006): "Basic principles in the planning of clinical trials in surgical oncology", European Surgery 38:27-32. doi:10.1007/s10353-006-0211-6, Level: beginner

Moreover, on the following pages we provide links to external collections of tutorials and to freely available books on statistical modelling and causal inference:

External Collections

Freely Available Books